diff --git a/plotly/_subplots.py b/plotly/_subplots.py
index 16a3958637..5aa3bba1dc 100644
--- a/plotly/_subplots.py
+++ b/plotly/_subplots.py
@@ -57,6 +57,7 @@ def make_subplots(
     row_titles=None,
     x_title=None,
     y_title=None,
+    font=dict(size=16),
     figure=None,
     **kwargs,
 ):
@@ -227,6 +228,9 @@ def make_subplots(
         Title to place to the left of the left column of subplots,
         centered vertically
 
+    font: dict (default dict(size=16))
+        Font used by any title of the subplots.
+
     figure: go.Figure or None (default None)
         If None, a new go.Figure instance will be created and its axes will be
         populated with those corresponding to the requested subplot geometry and
@@ -814,7 +818,7 @@ def _check_hv_spacing(dimsize, spacing, name, dimvarname, dimname):
 
     # Add subplot titles
     plot_title_annotations = _build_subplot_title_annotations(
-        subplot_titles, list_of_domains
+        subplot_titles, list_of_domains, font = font
     )
 
     layout["annotations"] = plot_title_annotations
@@ -835,7 +839,7 @@ def _check_hv_spacing(dimsize, spacing, name, dimvarname, dimname):
 
         # Add subplot titles
         column_title_annotations = _build_subplot_title_annotations(
-            column_titles, domains_list
+            column_titles, domains_list, font = font
         )
 
         layout["annotations"] += tuple(column_title_annotations)
@@ -849,7 +853,7 @@ def _check_hv_spacing(dimsize, spacing, name, dimvarname, dimname):
 
         # Add subplot titles
         column_title_annotations = _build_subplot_title_annotations(
-            row_titles, domains_list, title_edge="right"
+            row_titles, domains_list, title_edge="right", font = font
         )
 
         layout["annotations"] += tuple(column_title_annotations)
@@ -859,7 +863,7 @@ def _check_hv_spacing(dimsize, spacing, name, dimvarname, dimname):
 
         # Add subplot titles
         column_title_annotations = _build_subplot_title_annotations(
-            [x_title], domains_list, title_edge="bottom", offset=30
+            [x_title], domains_list, title_edge="bottom", offset=30, font = font
         )
 
         layout["annotations"] += tuple(column_title_annotations)
@@ -869,7 +873,7 @@ def _check_hv_spacing(dimsize, spacing, name, dimvarname, dimname):
 
         # Add subplot titles
         column_title_annotations = _build_subplot_title_annotations(
-            [y_title], domains_list, title_edge="left", offset=40
+            [y_title], domains_list, title_edge="left", offset=40, font = font
         )
 
         layout["annotations"] += tuple(column_title_annotations)
@@ -1163,7 +1167,7 @@ def _get_cartesian_label(x_or_y, r, c, cnt):
 
 
 def _build_subplot_title_annotations(
-    subplot_titles, list_of_domains, title_edge="top", offset=0
+    subplot_titles, list_of_domains, title_edge="top", offset=0, font=dict(size=16)
 ):
     # If shared_axes is False (default) use list_of_domains
     # This is used for insets and irregular layouts
@@ -1236,7 +1240,7 @@ def _build_subplot_title_annotations(
                 "yref": "paper",
                 "text": subplot_titles[index],
                 "showarrow": False,
-                "font": dict(size=16),
+                "font": font,
                 "xanchor": xanchor,
                 "yanchor": yanchor,
             }