diff --git a/newrelic/config.py b/newrelic/config.py
index 21ce996f6c..c2b7b5c2d6 100644
--- a/newrelic/config.py
+++ b/newrelic/config.py
@@ -2084,6 +2084,10 @@ def _process_module_builtin_defaults():
         "asyncio.base_events", "newrelic.hooks.coroutines_asyncio", "instrument_asyncio_base_events"
     )
 
+    _process_module_definition("asyncio.events", "newrelic.hooks.coroutines_asyncio", "instrument_asyncio_events")
+
+    _process_module_definition("asyncio.runners", "newrelic.hooks.coroutines_asyncio", "instrument_asyncio_runners")
+
     _process_module_definition(
         "langchain_core.runnables.base",
         "newrelic.hooks.mlmodel_langchain",
@@ -2671,8 +2675,6 @@ def _process_module_builtin_defaults():
         "langchain_core.callbacks.manager", "newrelic.hooks.mlmodel_langchain", "instrument_langchain_callbacks_manager"
     )
 
-    _process_module_definition("asyncio.events", "newrelic.hooks.coroutines_asyncio", "instrument_asyncio_events")
-
     _process_module_definition("asgiref.sync", "newrelic.hooks.adapter_asgiref", "instrument_asgiref_sync")
 
     _process_module_definition(
diff --git a/newrelic/hooks/coroutines_asyncio.py b/newrelic/hooks/coroutines_asyncio.py
index 41fc776595..72bb2e7fc8 100644
--- a/newrelic/hooks/coroutines_asyncio.py
+++ b/newrelic/hooks/coroutines_asyncio.py
@@ -16,36 +16,73 @@
 from newrelic.core.trace_cache import trace_cache
 
 
-def remove_from_cache(task):
+def remove_from_cache_callback(task):
     cache = trace_cache()
     cache.task_stop(task)
 
 
-def propagate_task_context(task):
+def wrap_create_task(task):
     trace_cache().task_start(task)
-    task.add_done_callback(remove_from_cache)
+    task.add_done_callback(remove_from_cache_callback)
     return task
 
 
-def _bind_loop(loop, *args, **kwargs):
+def _instrument_event_loop(loop):
+    if loop and hasattr(loop, "create_task") and not hasattr(loop.create_task, "__wrapped__"):
+        wrap_out_function(loop, "create_task", wrap_create_task)
+
+
+def _bind_set_event_loop(loop, *args, **kwargs):
     return loop
 
 
-def wrap_create_task(wrapped, instance, args, kwargs):
-    loop = _bind_loop(*args, **kwargs)
+def wrap_set_event_loop(wrapped, instance, args, kwargs):
+    loop = _bind_set_event_loop(*args, **kwargs)
 
-    if loop and not hasattr(loop.create_task, "__wrapped__"):
-        wrap_out_function(loop, "create_task", propagate_task_context)
+    _instrument_event_loop(loop)
 
     return wrapped(*args, **kwargs)
 
 
+def wrap__lazy_init(wrapped, instance, args, kwargs):
+    result = wrapped(*args, **kwargs)
+    # This logic can be used for uvloop, but should
+    # work for any valid custom loop factory.
+
+    # A custom loop_factory will be used to create
+    # a new event loop instance.  It will then run
+    # the main() coroutine on this event loop.  Once
+    # this coroutine is complete, the event loop will
+    # be stopped and closed.
+
+    # The new loop that is created and set as the
+    # running loop of the duration of the run() call.
+    # When the coroutine starts, it runs in the context
+    # that was active when run() was called.  Any tasks
+    # created within this coroutine on this new event
+    # loop will inherit that context.
+
+    # Note: The loop created by loop_factory is never
+    # set as the global current loop for the thread,
+    # even while it is running.
+    loop = instance._loop
+    _instrument_event_loop(loop)
+
+    return result
+
+
 def instrument_asyncio_base_events(module):
-    wrap_out_function(module, "BaseEventLoop.create_task", propagate_task_context)
+    wrap_out_function(module, "BaseEventLoop.create_task", wrap_create_task)
 
 
 def instrument_asyncio_events(module):
     if hasattr(module, "_BaseDefaultEventLoopPolicy"):  # Python >= 3.14
-        wrap_function_wrapper(module, "_BaseDefaultEventLoopPolicy.set_event_loop", wrap_create_task)
+        wrap_function_wrapper(module, "_BaseDefaultEventLoopPolicy.set_event_loop", wrap_set_event_loop)
     else:  # Python <= 3.13
-        wrap_function_wrapper(module, "BaseDefaultEventLoopPolicy.set_event_loop", wrap_create_task)
+        wrap_function_wrapper(module, "BaseDefaultEventLoopPolicy.set_event_loop", wrap_set_event_loop)
+
+
+# For Python >= 3.11
+def instrument_asyncio_runners(module):
+    if hasattr(module, "Runner") and hasattr(module.Runner, "_lazy_init"):
+        wrap_function_wrapper(module, "Runner._lazy_init", wrap__lazy_init)
diff --git a/tests/adapter_uvicorn/test_uvicorn.py b/tests/adapter_uvicorn/test_uvicorn.py
index 0084be3e46..d5db2d6ca6 100644
--- a/tests/adapter_uvicorn/test_uvicorn.py
+++ b/tests/adapter_uvicorn/test_uvicorn.py
@@ -56,8 +56,8 @@ def app(request):
     return request.param
 
 
-@pytest.fixture
-def port(app):
+@pytest.fixture(params=["asyncio", "uvloop", "none"], ids=["asyncio", "uvloop", "none"])
+def port(app, request):
     port = get_open_port()
 
     loops = []
@@ -72,7 +72,7 @@ def on_tick_sync():
         async def on_tick():
             on_tick_sync()
 
-        config = Config(app, host="127.0.0.1", port=port, loop="asyncio")
+        config = Config(app, host="127.0.0.1", port=port, loop=request.param)
         config.callback_notify = on_tick
         config.log_config = {"version": 1}
         config.disable_lifespan = True
diff --git a/tests/coroutines_asyncio/test_context_propagation.py b/tests/coroutines_asyncio/test_context_propagation.py
index b338b6ec3e..eb5c358745 100644
--- a/tests/coroutines_asyncio/test_context_propagation.py
+++ b/tests/coroutines_asyncio/test_context_propagation.py
@@ -36,16 +36,31 @@
     import uvloop
 
     loop_policies = (pytest.param(None, id="asyncio"), pytest.param(uvloop.EventLoopPolicy(), id="uvloop"))
+    uvloop_factory = (pytest.param(uvloop.new_event_loop, id="uvloop"), pytest.param(None, id="None"))
 except ImportError:
     loop_policies = (pytest.param(None, id="asyncio"),)
+    uvloop_factory = (pytest.param(None, id="None"),)
+
+
+def loop_factories():
+    import asyncio
+
+    if sys.platform == "win32":
+        return (pytest.param(asyncio.ProactorEventLoop, id="asyncio.ProactorEventLoop"), *uvloop_factory)
+    else:
+        return (pytest.param(asyncio.SelectorEventLoop, id="asyncio.SelectorEventLoop"), *uvloop_factory)
 
 
 @pytest.fixture(autouse=True)
 def reset_event_loop():
-    from asyncio import set_event_loop, set_event_loop_policy
+    try:
+        from asyncio import set_event_loop, set_event_loop_policy
+
+        # Remove the loop policy to avoid side effects
+        set_event_loop_policy(None)
+    except ImportError:
+        from asyncio import set_event_loop
 
-    # Remove the loop policy to avoid side effects
-    set_event_loop_policy(None)
     set_event_loop(None)
 
 
@@ -102,6 +117,7 @@ async def _test(asyncio, schedule, nr_enabled=True):
     return trace
 
 
+@pytest.mark.skipif(sys.version_info >= (3, 16), reason="loop_policy is not available")
 @pytest.mark.parametrize("loop_policy", loop_policies)
 @pytest.mark.parametrize("schedule", ("create_task", "ensure_future"))
 @validate_transaction_metrics(
@@ -166,10 +182,12 @@ def handle_exception(loop, context):
         memcache_trace("cmd"),
     ],
 )
-def test_two_transactions(event_loop, trace):
+def test_two_transactions_with_global_event_loop(event_loop, trace):
     """
     Instantiate a coroutine in one transaction and await it in
     another. This should not cause any errors.
+    This uses the global event loop policy, which has been deprecated
+    since Python 3.11 and is scheduled for removal in Python 3.16.
     """
     import asyncio
 
@@ -211,6 +229,99 @@ async def await_task():
     event_loop.run_until_complete(asyncio.gather(afut, bfut))
 
 
+@pytest.mark.skipif(sys.version_info < (3, 11), reason="asyncio.Runner is not available")
+@validate_transaction_metrics("await_task", background_task=True)
+@validate_transaction_metrics("create_coro", background_task=True, index=-2)
+@pytest.mark.parametrize("loop_factory", loop_factories())
+@pytest.mark.parametrize(
+    "trace",
+    [
+        function_trace(name="simple_gen"),
+        external_trace(library="lib", url="http://foo.com"),
+        database_trace("select * from foo"),
+        datastore_trace("lib", "foo", "bar"),
+        message_trace("lib", "op", "typ", "name"),
+        memcache_trace("cmd"),
+    ],
+)
+def test_two_transactions_with_loop_factory(trace, loop_factory):
+    """
+    Instantiate a coroutine in one transaction and await it in
+    another. This should not cause any errors.
+    Starting in Python 3.11, the asyncio.Runner class was added
+    as well as the loop_factory parameter.  The loop_factory
+    parameter provides a replacement for loop policies (which
+    are scheduled for removal in Python 3.16).
+    """
+    import asyncio
+
+    @trace
+    async def task():
+        pass
+
+    @background_task(name="create_coro")
+    async def create_coro():
+        return asyncio.create_task(task())
+
+    @background_task(name="await_task")
+    async def await_task(task_to_await):
+        return await task_to_await
+
+    async def _main():
+        _task = await create_coro()
+        return await await_task(_task)
+
+    with asyncio.Runner(loop_factory=loop_factory) as runner:
+        runner.run(_main())
+
+
+@pytest.mark.skipif(sys.version_info < (3, 11), reason="loop_factory/asyncio.Runner is not available")
+@pytest.mark.parametrize("loop_factory", loop_factories())
+@validate_transaction_metrics(
+    "test_context_propagation:test_context_propagation_with_loop_factory",
+    background_task=True,
+    scoped_metrics=(("Function/waiter2", 2), ("Function/waiter3", 2)),
+)
+@background_task()
+def test_context_propagation_with_loop_factory(loop_factory):
+    import asyncio
+
+    exceptions = []
+
+    def handle_exception(loop, context):
+        exceptions.append(context)
+
+        # Call default handler for standard logging
+        loop.default_exception_handler(context)
+
+    async def subtask():
+        with FunctionTrace(name="waiter2", terminal=True):
+            pass
+
+        await child()
+
+    async def _task(trace):
+        assert current_trace() == trace
+
+        await subtask()
+
+    trace = current_trace()
+
+    with asyncio.Runner(loop_factory=loop_factory) as runner:
+        assert trace == current_trace()
+        runner._loop.set_exception_handler(handle_exception)
+        runner.run(_task(trace))
+        runner.run(_task(trace))
+
+    # The agent should have removed all traces from the cache since
+    # run_until_complete has terminated (all callbacks scheduled inside the
+    # task have run)
+    assert len(trace_cache()) == 1  # Sentinel is all that remains
+
+    # # Assert that no exceptions have occurred
+    assert not exceptions, exceptions
+
+
 # Sentinel left in cache transaction exited
 async def sentinel_in_cache_txn_exited(asyncio, bg):
     event = asyncio.Event()
diff --git a/tox.ini b/tox.ini
index e27ce2ef83..98cea6ee29 100644
--- a/tox.ini
+++ b/tox.ini
@@ -116,8 +116,8 @@ envlist =
     python-adapter_hypercorn-{py310,py311,py312,py313,py314}-hypercornlatest,
     python-adapter_hypercorn-{py38,py39}-hypercorn{0010,0011,0012,0013},
     python-adapter_mcp-{py310,py311,py312,py313,py314},
-    python-adapter_uvicorn-{py38,py39,py310,py311,py312,py313,py314}-uvicornlatest,
-    python-adapter_uvicorn-py38-uvicorn014,
+    python-adapter_uvicorn-{py39,py310,py311,py312,py313,py314}-uvicornlatest,
+    python-adapter_uvicorn-py38-uvicorn020,
     python-adapter_waitress-{py38,py39,py310,py311,py312,py313,py314}-waitresslatest,
     python-application_celery-{py38,py39,py310,py311,py312,py313,py314,pypy311}-celerylatest,
     python-application_celery-py311-celery{0504,0503,0502},
@@ -239,9 +239,11 @@ deps =
     adapter_hypercorn-hypercorn0010: hypercorn[h3]<0.11
     adapter_hypercorn: niquests
     adapter_mcp: fastmcp
-    adapter_uvicorn-uvicorn014: uvicorn<0.15
+    adapter_uvicorn-uvicorn020: uvicorn<0.21
+    adapter_uvicorn-uvicorn020: uvloop<0.20
     adapter_uvicorn-uvicornlatest: uvicorn
     adapter_uvicorn: typing-extensions
+    adapter_uvicorn: uvloop
     adapter_waitress: WSGIProxy2
     adapter_waitress-waitresslatest: waitress
     agent_features: beautifulsoup4