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2 | 2 | <!-- README.md is generated from README.Rmd. Please edit that file --> |
| 3 | +<!-- [](https://zenodo.org/badge/latestdoi/331070175) --> |
3 | 4 |
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4 | | -# An Introductory Tutorial to Cohort State-Transition Models in R |
| 5 | +# An Introductory Tutorial on Cohort State-Transition Models in R Using a Cost-Effectiveness Analysis Example |
| 6 | + |
| 7 | +This GitHub repository provides the code of the tutorial on how to |
| 8 | +implement time-dependent cohort state-transition models (cSTMs) in R |
| 9 | +using a cost-effectiveness analysis (CEA) example, explained in the |
| 10 | +following manuscript: |
| 11 | + |
| 12 | +- Alarid-Escudero F, Krijkamp EM, Enns EA, Yang A, Hunink MGM, |
| 13 | + Pechlivanoglou P, Jalal H. [An Introductory Tutorial on Cohort |
| 14 | + State-Transition Models in R Using a Cost-Effectiveness Analysis |
| 15 | + Example](http://arxiv.org/abs/2001.07824). arXiv:200107824v3. |
| 16 | + 2021:1-26. |
| 17 | + |
| 18 | +The |
| 19 | +[`R`](https://github.com/DARTH-git/cohort-modeling-tutorial-intro/tree/main/R) |
| 20 | +folder includes two different scripts corresponding to functions used to |
| 21 | +synthesize cSTMs outputs and conduct several sensitivity analyses: - |
| 22 | +[`Funtions.R`](https://github.com/DARTH-git/cohort-modeling-tutorial-intro/blob/main/R/Functions.R): |
| 23 | +Functions to generate epidemiological measures from time-dependent |
| 24 | +cSTMs. - |
| 25 | +[`Functions_cSTM_time_indep.R`](https://github.com/DARTH-git/cohort-modeling-tutorial-intro/blob/main/R/Functions_cSTM_time_indep.R): |
| 26 | +These functions wrap the time-dependent cSTM, compute CEA measures, and |
| 27 | +generate probabilistic sensitivity analysis (PSA) input datasets. |
| 28 | + |
| 29 | +We recommend familiarizing with the [DARTH](http://darthworkgroup.com) |
| 30 | +coding framework described in |
| 31 | + |
| 32 | +- Alarid-Escudero F, Krijkamp EM, Pechlivanoglou P, Jalal HJ, Kao SYZ, |
| 33 | + Yang A, Enns EA. [A Need for Change! A Coding Framework for |
| 34 | + Improving Transparency in Decision |
| 35 | + Modeling](https://link.springer.com/article/10.1007/s40273-019-00837-x). |
| 36 | + [PharmacoEconomics](https://www.springer.com/journal/40273), |
| 37 | + 2190;37(11):1329–1339. <https://doi.org/10.1007/s40273-019-00837-x> |
| 38 | + |
| 39 | +To run the CEA, you require [`dampack`: Decision-Analytic Modeling |
| 40 | +Package](https://cran.r-project.org/web/packages/dampack/index.html), an |
| 41 | +R package for analyzing and visualizing the health economic outputs of |
| 42 | +decision models. |
| 43 | + |
| 44 | +## Full list of Contributors: |
| 45 | + |
| 46 | +- [Fernando Alarid-Escudero](https://github.com/feralaes) |
| 47 | + |
| 48 | +- [Eline Krijkamp](https://github.com/krijkamp) |
| 49 | + |
| 50 | +- [Eva Enns](https://github.com/evaenns) |
| 51 | + |
| 52 | +- [Alan Yang](https://github.com/alanyang0924) |
| 53 | + |
| 54 | +- [Myriam |
| 55 | + Hunink](http://www.erasmus-epidemiology.nl/people/profile.php?id=45) |
| 56 | + |
| 57 | +- [Petros Pechlivanoglou](https://github.com/ppehli) |
| 58 | + |
| 59 | +- [Hawre Jalal](https://github.com/hjalal) |
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