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README.Rmd

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This GitHub repository provides the code of the tutorial on how to implement time-independent cohort state-transition models (cSTMs) in R using a cost-effectiveness analysis (CEA) example, explained in the following manuscript:
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- Alarid-Escudero F, Krijkamp EM, Enns EA, Yang A, Hunink MGM, Pechlivanoglou P, Jalal H. [An Introductory Tutorial on Cohort State-Transition Models in R Using a Cost-Effectiveness Analysis Example](http://arxiv.org/abs/2001.07824). arXiv:200107824v3. 2021:1-26.
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- Alarid-Escudero F, Krijkamp EM, Enns EA, Yang A, Hunink MGM, Pechlivanoglou P, Jalal H. [An Introductory Tutorial on Cohort State-Transition Models in R Using a Cost-Effectiveness Analysis Example](http://arxiv.org/abs/2001.07824). arXiv:200107824v4. 2022:1-30.
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The release that accompanies the published article has been archived in zenodo: https://zenodo.org/badge/latestdoi/357362984
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The [`R`](https://github.com/DARTH-git/cohort-modeling-tutorial-intro/tree/main/R) folder includes two different scripts corresponding to functions used to synthesize cSTMs outputs and conduct several sensitivity analyses:
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- [`Funtions.R`](https://github.com/DARTH-git/cohort-modeling-tutorial-intro/blob/main/R/Functions.R): Functions to generate epidemiological measures from time-independent cSTMs.
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- [`Funtions.R`](https://github.com/DARTH-git/cohort-modeling-tutorial-intro/blob/main/R/Functions.R): Functions that generate epidemiological measures from time-independent cSTMs and compute within-cycle correction, parameter transformation, matrix checks, and CEA and PSA visualization.
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- [`Functions_cSTM_time_indep.R`](https://github.com/DARTH-git/cohort-modeling-tutorial-intro/blob/main/R/Functions_cSTM_time_indep.R): These functions wrap the time-independent cSTM, compute CEA measures, and generate probabilistic sensitivity analysis (PSA) input datasets.
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## How to cite this R code in your article
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You can cite the R code in this repository like this "we based our analysis using the R code from Alarid-Escudero F et al. (2021)". Here is the full bibliographic reference to include in your reference list for the manuscript and the R code (don't forget to update the 'last accessed' date):
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> Alarid-Escudero F, Krijkamp EM, Enns EA, Yang A, Hunink MGM, Pechlivanoglou P, Jalal H. An Introductory Tutorial on Cohort State-Transition Models in R Using a Cost-Effectiveness Analysis Example (http://arxiv.org/abs/2001.07824). arXiv:200107824v3. 2021:1-26.
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> Alarid-Escudero F, Krijkamp EM, Enns EA, Yang A, Hunink MGM, Pechlivanoglou P, Jalal H. An Introductory Tutorial on Cohort State-Transition Models in R Using a Cost-Effectiveness Analysis Example (http://arxiv.org/abs/2001.07824). arXiv:200107824v4. 2022:1-30.
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> Alarid-Escudero F, Krijkamp EM, Enns EA, Yang A, Hunink MGM, Pechlivanoglou P, Jalal H (2021). R Code for An Introductory Tutorial on Cohort State-Transition Models in R Using a Cost-Effectiveness Analysis Example (Version v0.1.1). Zenodo. [10.5281/zenodo.5223093](https://www.doi.org/10.5281/zenodo.5223093). Last accessed 19 August 2021.
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> Alarid-Escudero F, Krijkamp EM, Enns EA, Yang A, Hunink MGM, Pechlivanoglou P, Jalal H (2022). R Code for An Introductory Tutorial on Cohort State-Transition Models in R Using a Cost-Effectiveness Analysis Example (Version v0.1.1). Zenodo. [10.5281/zenodo.5223093](https://www.doi.org/10.5281/zenodo.5223093). Last accessed 30 March 2022.
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If you adapted the code, you should indicate "Adapted from:" or "Based on" so it is understood that you modified the code. For more information on how to cite computer code, we refer the user to review [Writing Code (from MIT Research Guide)](https://integrity.mit.edu/handbook/writing-code), which provides examples of how and when to cite computer code.
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README.md

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- Alarid-Escudero F, Krijkamp EM, Enns EA, Yang A, Hunink MGM,
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Pechlivanoglou P, Jalal H. [An Introductory Tutorial on Cohort
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State-Transition Models in R Using a Cost-Effectiveness Analysis
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Example](http://arxiv.org/abs/2001.07824). arXiv:200107824v3.
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2021:1-26.
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Example](http://arxiv.org/abs/2001.07824). arXiv:200107824v4.
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2022:1-30.
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The release that accompanies the published article has been archived in
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zenodo: <https://zenodo.org/badge/latestdoi/357362984>
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synthesize cSTMs outputs and conduct several sensitivity analyses:
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- [`Funtions.R`](https://github.com/DARTH-git/cohort-modeling-tutorial-intro/blob/main/R/Functions.R):
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Functions to generate epidemiological measures from time-independent
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cSTMs.
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Functions that generate epidemiological measures from
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time-independent cSTMs and compute within-cycle correction,
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parameter transformation, matrix checks, and CEA and PSA
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visualization.
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- [`Functions_cSTM_time_indep.R`](https://github.com/DARTH-git/cohort-modeling-tutorial-intro/blob/main/R/Functions_cSTM_time_indep.R):
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These functions wrap the time-independent cSTM, compute CEA
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measures, and generate probabilistic sensitivity analysis (PSA)
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> Alarid-Escudero F, Krijkamp EM, Enns EA, Yang A, Hunink MGM,
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> Pechlivanoglou P, Jalal H. An Introductory Tutorial on Cohort
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> State-Transition Models in R Using a Cost-Effectiveness Analysis
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> Example (<http://arxiv.org/abs/2001.07824>). arXiv:200107824v3.
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> 2021:1-26.
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> Example (<http://arxiv.org/abs/2001.07824>). arXiv:200107824v4.
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> 2022:1-30.
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> Alarid-Escudero F, Krijkamp EM, Enns EA, Yang A, Hunink MGM,
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> Pechlivanoglou P, Jalal H (2021). R Code for An Introductory Tutorial
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> Pechlivanoglou P, Jalal H (2022). R Code for An Introductory Tutorial
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> on Cohort State-Transition Models in R Using a Cost-Effectiveness
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> Analysis Example (Version v0.1.1). Zenodo.
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> [10.5281/zenodo.5223093](https://www.doi.org/10.5281/zenodo.5223093).
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> Last accessed 19 August 2021.
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> Last accessed 30 March 2022.
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If you adapted the code, you should indicate “Adapted from:” or “Based
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on” so it is understood that you modified the code. For more information

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